1 keywords

CATH Domain 4tydA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.10 Thrombin, subunit H
Homologous Superfamily 2.40.10.120  

Domain Context

CATH Clusters

Superfamily 2.40.10.120
Functional Family Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

Q0ZNA6
Q0ZNA6_9HEPC
Hepacivirus C
NS3 protease

PDB Structure

PDB 4TYD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.
Parsy, C., Alexandre, F.R., Brandt, G., Caillet, C., Cappelle, S., Chaves, D., Convard, T., Derock, M., Gloux, D., Griffon, Y., Lallos, L., Leroy, F., Liuzzi, M., Loi, A.G., Moulat, L., Musiu, C., Rahali, H., Roques, V., Seifer, M., Standring, D., Surleraux, D.
Bioorg.Med.Chem.Lett.