CATH Classification

Domain Context

CATH Clusters

Superfamily Neurotransmitter-gated ion-channel transmembrane domain
Functional Family Proton-gated ion channel

Enzyme Information

UniProtKB Entries (1)

P0C7B7
ELIC_DICCH
Dickeya chrysanthemi
Cys-loop ligand-gated ion channel

PDB Structure

PDB 4TWF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
Ulens, C., Spurny, R., Thompson, A.J., Alqazzaz, M., Debaveye, S., Han, L., Price, K., Villalgordo, J.M., Tresadern, G., Lynch, J.W., Lummis, S.C.
Structure