CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt P27001
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (2)

P27001
SYFA_THETH
Thermus thermophilus
Phenylalanine--tRNA ligase alpha subunit
Q5SGX1
SYFB_THET8
Thermus thermophilus HB8
Phenylalanine--tRNA ligase beta subunit

PDB Structure

PDB 4TVA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Universal pathway for posttransfer editing reactions: Insights from the crystal structure of TtPheRS with puromycin.
Tworowski, D., Klipcan, L., Peretz, M., Moor, N., Safro, M.G.
Proc.Natl.Acad.Sci.USA