CATH Classification

Domain Context

CATH Clusters

Superfamily DNA polymerase, Y-family, little finger domain
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q97W02
DPO4_SACS2
Saccharolobus solfataricus P2
DNA polymerase IV

PDB Structure

PDB 4TQR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Xu, W., Ouellette, A.M., Wawrzak, Z., Shriver, S.J., Anderson, S.M., Zhao, L.
Biochemistry