CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

UniProtKB Entries (1)

A5K8L9
A5K8L9_PLAVS
Plasmodium vivax Sal-1
Serine hydroxymethyltransferase, putative

PDB Structure

PDB 4TMR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT): Cocrystal Structures of Pyrazolopyrans with Potent Blood- and Liver-Stage Activities.
Witschel, M.C., Rottmann, M., Schwab, A., Leartsakulpanich, U., Chitnumsub, P., Seet, M., Tonazzi, S., Schwertz, G., Stelzer, F., Mietzner, T., McNamara, C., Thater, F., Freymond, C., Jaruwat, A., Pinthong, C., Riangrungroj, P., Oufir, M., Hamburger, M., Maser, P., Sanz-Alonso, L.M., Charman, S., Wittlin, S., Yuthavong, Y., Chaiyen, P., Diederich, F.
J.Med.Chem.