CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.40.20
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q97W02
DPO4_SULSO
Sulfolobus solfataricus P2
DNA polymerase IV

PDB Structure

PDB 4RUC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
Patra, A., Banerjee, S., Johnson Salyard, T.L., Malik, C.K., Christov, P.P., Rizzo, C.J., Stone, M.P., Egli, M.
J.Am.Chem.Soc.