CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.220 | predicted glycosyltransferase like domains |
Domain Context
CATH Clusters
| Superfamily | predicted glycosyltransferase like domains |
| Functional Family |
Enzyme Information
| 2.4.1.33 |
Mannuronan synthase.
based on mapping to UniProt Q9HY69
GDP-alpha-D-mannuronate + ((1->4)-beta-D-mannuronosyl)(n) = GDP + ((1->4)-beta-D-mannuronosyl)(n+1).
-!- The enzyme catalyzes the polymerization of beta-D-mannuronate residues into a mannuronan polymer, an intermediate in the biosynthesis of alginate. -!- It is found in brown algae and in alginate-producing bacterial species from the Pseudomonas and Azotobacter genera.
|
UniProtKB Entries (1)
| Q9HY69 |
ALG44_PSEAE
Pseudomonas aeruginosa PAO1
Mannuronan synthase
|
PDB Structure
| PDB | 4RT0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa.
J.Biol.Chem.
|