CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.10 | Jelly Rolls |
Domain Context
CATH Clusters
| Superfamily | Jelly Rolls |
| Functional Family |
Enzyme Information
| 1.14.11.63 |
Peptidyl-lysine (3S)-dioxygenase.
based on mapping to UniProt P0C872
A [protein]-L-lysine + 2-oxoglutarate + O(2) = a [protein]-(3S)-hydroxy- L-lysine + succinate + CO(2).
-!- Requires iron(II). -!- The enzyme acts on specific lysine residues in its substrates, and is stereo-specific. -!- The enzyme encoded by the human JMJD7 gene acts specifically on two related members of the translation factor family of GTPases, DRG1 and DRG2.
|
| 3.4.-.- |
Acting on peptide bonds (peptidases).
based on mapping to UniProt P0C872
|
UniProtKB Entries (1)
| P0C872 |
JMJD7_MOUSE
Mus musculus
Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7
|
PDB Structure
| PDB | 4QU2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of JMJD7 with alpha-KG
To be Published
|