CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family serine/threonine-protein kinase haspin

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8TF76
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q8TF76
HASP_HUMAN
Homo sapiens
Serine/threonine-protein kinase haspin

PDB Structure

PDB 4QTC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics.
Chaikuad, A., M C Tacconi, E., Zimmer, J., Liang, Y., Gray, N.S., Tarsounas, M., Knapp, S.
Nat.Chem.Biol.