CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidyl-tRNA hydrolase
Functional Family Peptidyl-tRNA hydrolase family protein

Enzyme Information

3.1.1.29
Aminoacyl-tRNA hydrolase.
based on mapping to UniProt B5XIP6
N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA.

UniProtKB Entries (1)

B5XIP6
PTH_STRPZ
Streptococcus pyogenes NZ131
Peptidyl-tRNA hydrolase

PDB Structure

PDB 4QT4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, Streptococcus pyogenes at 2.19 angstrom resolution shows the closed structure of the substrate-binding cleft.
Singh, A., Gautam, L., Sinha, M., Bhushan, A., Kaur, P., Sharma, S., Singh, T.P.
FEBS Open Bio