CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Bifunctional dTDP-4-dehydrorhamnose 3,5-epimerase/dTDP-4-dehydrorhamnose reductase |
Enzyme Information
| 5.1.3.13 |
dTDP-4-dehydrorhamnose 3,5-epimerase.
based on mapping to UniProt Q9LQ04
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose.
-!- Occurs in a complex with EC 1.1.1.133.
|
| 1.1.1.133 |
dTDP-4-dehydrorhamnose reductase.
based on mapping to UniProt Q9LQ04
dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + NADPH.
-!- In the reverse direction, reduction on the 4-position of the hexose moiety takes place only while the substrate is bound to another enzyme that catalyzes epimerization at C-3 and C-5; the complex has been referred to as dTDP-L-rhamnose synthase.
|
UniProtKB Entries (1)
| Q9LQ04 |
RMLCD_ARATH
Arabidopsis thaliana
Bifunctional dTDP-4-dehydrorhamnose 3,5-epimerase/dTDP-4-dehydrorhamnose reductase
|
PDB Structure
| PDB | 4QQR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insight into nucleotide rhamnose synthase/epimerase-reductase from Arabidopsis thaliana
To be Published
|