CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.130.20
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O43683
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O43683
BUB1_HUMAN
Homo sapiens
Mitotic checkpoint serine/threonine-protein kinase BUB1

PDB Structure

PDB 4QPM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting.
Lin, Z., Jia, L., Tomchick, D.R., Luo, X., Yu, H.
Structure