CATH Classification

Domain Context

CATH Clusters

Superfamily Imidazole glycerol phosphate dehydratase; domain 1
Functional Family Imidazoleglycerol-phosphate dehydratase HisB

Enzyme Information

4.2.1.19
Imidazoleglycerol-phosphate dehydratase.
based on mapping to UniProt O23346
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.

UniProtKB Entries (1)

O23346
HIS5B_ARATH
Arabidopsis thaliana
Imidazoleglycerol-phosphate dehydratase 2, chloroplastic

PDB Structure

PDB 4QNJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Bisson, C., Britton, K.L., Sedelnikova, S.E., Rodgers, H.F., Eadsforth, T.C., Viner, R.C., Hawkes, T.R., Baker, P.J., Rice, D.W.
Structure