CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family WD repeat-containing protein 5

Enzyme Information

UniProtKB Entries (1)

P61964
WDR5_HUMAN
Homo sapiens
WD repeat-containing protein 5

PDB Structure

PDB 4QL1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia.
Grebien, F., Vedadi, M., Getlik, M., Giambruno, R., Grover, A., Avellino, R., Skucha, A., Vittori, S., Kuznetsova, E., Smil, D., Barsyte-Lovejoy, D., Li, F., Poda, G., Schapira, M., Wu, H., Dong, A., Senisterra, G., Stukalov, A., Huber, K.V., Schonegger, A., Marcellus, R., Bilban, M., Bock, C., Brown, P.J., Zuber, J., Bennett, K.L., Al-Awar, R., Delwel, R., Nerlov, C., Arrowsmith, C.H., Superti-Furga, G.
Nat.Chem.Biol.