CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tyrosine--tRNA ligase

Enzyme Information

6.1.1.1
Tyrosine--tRNA ligase.
based on mapping to UniProt P54577
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).

UniProtKB Entries (1)

P54577
SYYC_HUMAN
Homo sapiens
Tyrosine--tRNA ligase, cytoplasmic

PDB Structure

PDB 4Q93
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Sajish, M., Schimmel, P.
Nature