CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.429 | Macrophage Migration Inhibitory Factor |
|
3.30.429.10 | Macrophage Migration Inhibitory Factor |
Domain Context
CATH Clusters
| Superfamily | Macrophage Migration Inhibitory Factor |
| Functional Family | D-dopachrome decarboxylase |
Enzyme Information
| 4.1.1.84 |
D-dopachrome decarboxylase.
based on mapping to UniProt P30046
D-dopachrome = 5,6-dihydroxyindole + CO(2).
-!- Specific for D-dopachrome as substrate. -!- L-dopachrome, L- or D-alpha-methyldopachrome and dopaminochrome do not act as substrates (see also EC 5.3.3.12).
|
UniProtKB Entries (1)
| P30046 |
DOPD_HUMAN
Homo sapiens
D-dopachrome decarboxylase
|
PDB Structure
| PDB | 4Q3F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.
Faseb J.
|