CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.450
Functional Family 2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Enzyme Information

3.2.2.-
Hydrolyzing N-glycosyl compounds.
based on mapping to UniProt O35820

UniProtKB Entries (1)

O35820
DNPH1_RAT
Rattus norvegicus
2'-deoxynucleoside 5'-phosphate N-hydrolase 1

PDB Structure

PDB 4P5D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities.
Amiable, C., Paoletti, J., Haouz, A., Padilla, A., Labesse, G., Kaminski, P.A., Pochet, S.
Eur.J.Med.Chem.