CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.8 | Phosphoenolpyruvate Carboxykinase; domain 2 |
|
2.170.8.10 | Phosphoenolpyruvate Carboxykinase, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Phosphoenolpyruvate Carboxykinase, domain 2 |
| Functional Family | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
Enzyme Information
| 4.1.1.32 |
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P07379
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.
|
UniProtKB Entries (1)
| P07379 |
PCKGC_RAT
Rattus norvegicus
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
|
PDB Structure
| PDB | 4OX2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.
Mol.Genet.Metab.
|