1 keywords

CATH Domain 4ovuB02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.287 Helix Hairpins
Homologous Superfamily 1.10.287.1490  

Domain Context

CATH Clusters

Superfamily 1.10.287.1490
Functional Family Putative phosphatidylinositol 3-kinase regulatory subunit alpha

Enzyme Information

UniProtKB Entries (1)

P42336
PK3CA_HUMAN
Homo sapiens
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

PDB Structure

PDB 4OVU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of nSH2 regulation and lipid binding in PI3K alpha.
Miller, M.S., Schmidt-Kittler, O., Bolduc, D.M., Brower, E.T., Chaves-Moreira, D., Allaire, M., Kinzler, K.W., Jennings, I.G., Thompson, P.E., Cole, P.A., Amzel, L.M., Vogelstein, B., Gabelli, S.B.
Oncotarget