CATH Classification

Domain Context

CATH Clusters

Superfamily CDGSH iron-sulfur domain, mitoNEET-type
Functional Family CDGSH iron-sulfur domain-containing protein 1

Enzyme Information

UniProtKB Entries (1)

Q8N5K1
CISD2_HUMAN
Homo sapiens
CDGSH iron-sulfur domain-containing protein 2

PDB Structure

PDB 4OOA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Tamir, S., Eisenberg-Domovich, Y., Conlan, A.R., Stofleth, J.T., Lipper, C.H., Paddock, M.L., Mittler, R., Jennings, P.A., Livnah, O., Nechushtai, R.
Acta Crystallogr.,Sect.D