CATH Domain 4onaA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.510	Transferase(Phosphotransferase); domain 1
	1.10.510.10	Transferase(Phosphotransferase) domain 1

Domain Context

CATH Clusters

Superfamily	Transferase(Phosphotransferase) domain 1
Functional Family	Calmodulin-domain protein kinase 1

Enzyme Information

UniProtKB Entries (1)

Q9BJF5_TOXGO

Toxoplasma gondii

Calmodulin-domain protein kinase 1

PDB Structure

PDB	4ONA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold. Zhang, Z., Ojo, K.K., Vidadala, R., Huang, W., Geiger, J.A., Scheele, S., Choi, R., Reid, M.C., Keyloun, K.R., Rivas, K., Siddaramaiah, L.K., Comess, K.M., Robinson, K.P., Merta, P.J., Kifle, L., Hol, W.G., Parsons, M., Merritt, E.A., Maly, D.J., Verlinde, C.L., Van Voorhis, W.C., Fan, E. ACS Med Chem Lett