CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.565 | Retinoid X Receptor |
|
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
| Superfamily | Retinoid X Receptor |
| Functional Family | Bile acid receptor isoform 4 |
Enzyme Information
UniProtKB Entries (1)
| Q96RI1 |
NR1H4_HUMAN
Homo sapiens
Bile acid receptor
|
PDB Structure
| PDB | 4OIV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha ) in Stabilizing the Homodimerization of the Receptor.
J.Biol.Chem.
|