CATH Domain 4ohoA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10490	Glucose-6-phosphate isomerase like protein; domain 1

Domain Context

CATH Clusters

Superfamily	Glucose-6-phosphate isomerase like protein; domain 1
Functional Family	Glucokinase regulatory protein

Enzyme Information

UniProtKB Entries (1)

GCKR_HUMAN

Homo sapiens

Glucokinase regulatory protein

PDB Structure

PDB	4OHO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series. Nishimura, N., Norman, M.H., Liu, L., Yang, K.C., Ashton, K.S., Bartberger, M.D., Chmait, S., Chen, J., Cupples, R., Fotsch, C., Helmering, J., Jordan, S.R., Kunz, R.K., Pennington, L.D., Poon, S.F., Siegmund, A., Sivits, G., Lloyd, D.J., Hale, C., St Jean, D.J. J.Med.Chem.