CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Phosphoribosylaminoimidazole-succinocarboxamide synthase

Enzyme Information

6.3.2.6
Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
based on mapping to UniProt O57978
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate.
-!- Forms part of the purine biosynthesis pathway.

UniProtKB Entries (1)

O57978
PUR7_PYRHO
Pyrococcus horikoshii OT3
Phosphoribosylaminoimidazole-succinocarboxamide synthase

PDB Structure

PDB 4O7S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
SAICAR synthetase (Type-2) in complex with TMP/TDP
Manjunath, K., Jeyakanthan, J., Sekar, K.
To be Published