CATH Classification

Domain Context

CATH Clusters

Superfamily Histidine kinase-like ATPase, C-terminal domain
Functional Family Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

P07900
HS90A_HUMAN
Homo sapiens
Heat shock protein HSP 90-alpha

PDB Structure

PDB 4O05
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of Novel HSP90 alpha / beta Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration of Potential Utility in Treating CNS Disorders such as Huntington's Disease.
Ernst, J.T., Neubert, T., Liu, M., Sperry, S., Zuccola, H., Turnbull, A., Fleck, B., Kargo, W., Woody, L., Chiang, P., Tran, D., Chen, W., Snyder, P., Alcacio, T., Nezami, A., Reynolds, J., Alvi, K., Goulet, L., Stamos, D.
J.Med.Chem.