CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 1.3.1.39 |
Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific).
based on mapping to UniProt A0A0H2XIJ1
An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADPH.
-!- This enzyme completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to an acyl- carrier protein. -!- It is one of the activities of EC 2.3.1.85. -!- The mammalian enzyme is Re-specific with respect to NADP(+) (cf. EC 1.3.1.10 and and EC 1.3.1.104).
|
UniProtKB Entries (1)
| A0A0H2XIJ1 |
A0A0H2XIJ1_STAA3
Staphylococcus aureus subsp. aureus USA300
Enoyl-[acyl-carrier-protein] reductase [NADPH]
|
PDB Structure
| PDB | 4NZ9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
To be published
To be Published
|
