CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Histone acetyltransferase p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q92793
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q92793
CBP_HUMAN
Homo sapiens
CREB-binding protein

PDB Structure

PDB 4NYV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Bromodomain of human CREBBP in complex with a quinazolin-one ligand
Filippakopoulos, P., Picaud, S., Felletar, I., Fedorov, O., Martin, S., Monteiro, O.P., von Delft, F., Brennan, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S.
TO BE PUBLISHED