CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Phosphoribosylaminoimidazole-succinocarboxamide synthase

Enzyme Information

6.3.2.6
Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
based on mapping to UniProt Q07296
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate.
-!- Forms part of the purine biosynthesis pathway.

UniProtKB Entries (1)

Q07296
PUR7_STRPN
Streptococcus pneumoniae TIGR4
Phosphoribosylaminoimidazole-succinocarboxamide synthase

PDB Structure

PDB 4NYE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg(2+), AIR and Asp.
Wolf, N.M., Abad-Zapatero, C., Johnson, M.E., Fung, L.W.
Acta Crystallogr.,Sect.D