CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1000 | HAD superfamily/HAD-like |
Domain Context
CATH Clusters
| Superfamily | HAD superfamily/HAD-like |
| Functional Family | Cytosolic 5-nucleotidase 3-like |
Enzyme Information
| 3.1.3.5 |
5'-nucleotidase.
based on mapping to UniProt Q9W197
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
-!- Wide specificity for 5'-nucleotides.
|
| 3.1.3.91 |
7-methylguanosine nucleotidase.
based on mapping to UniProt Q9W197
(1) N(7)-methyl-GMP + H(2)O = N(7)-methyl-guanosine + phosphate. (2) CMP + H(2)O = cytidine + phosphate.
-!- The enzyme also has low activity with N(7)-methyl-GDP, producing N(7)-methyl-GMP. -!- Does not accept AMP or GMP, and has low activity with UMP.
|
UniProtKB Entries (1)
| Q9W197 |
5NT3B_DROME
Drosophila melanogaster
7-methylguanosine phosphate-specific 5'-nucleotidase
|
PDB Structure
| PDB | 4NWI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP
Plos One
|