CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.50
Lysyl endopeptidase.
based on mapping to UniProt Q7M135
Preferential cleavage: Lys-|-Xaa, including Lys-|-Pro.
-!- Isolated from Achromobacter lyticus. -!- Enzymes with similar specificity are produced by Lysobacter enzymogenes (endoproteinase Lys-C) and Pseudomonas aeruginosa (Ps-1). -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

Q7M135
LYSC_LYSEN
Lysobacter enzymogenes
Lysyl endopeptidase

PDB Structure

PDB 4NSY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Atomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion hole.
Asztalos, P., Muller, A., Holke, W., Sobek, H., Rudolph, M.G.
Acta Crystallogr.,Sect.D