CATH Classification

Domain Context

CATH Clusters

Superfamily Single-stranded right-handed beta-helix, Pectin lyase-like
Functional Family

Enzyme Information

5.1.3.37
Mannuronan 5-epimerase.
based on mapping to UniProt Q887Q3
(Mannuronan)-beta-D-mannuronate = (alginate)-alpha-L-guluronate.
-!- The enzyme epimerizes the C-5 bond in some beta-D-mannuronate residues in mannuronan, converting them to alpha-L-guluronate residues, and thus modifying the mannuronan into alginate. -!- It is found in brown algae and alginate-producing bacterial species from the Pseudomonas and Azotobacter genera.

UniProtKB Entries (1)

Q887Q3
ALGG_PSESM
Pseudomonas syringae pv. tomato str. DC3000
Mannuronan C5-epimerase

PDB Structure

PDB 4NK8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Catalytic Mechanism and Mode of Action of the Periplasmic Alginate Epimerase AlgG.
Wolfram, F., Kitova, E.N., Robinson, H., Walvoort, M.T., Codee, J.D., Klassen, J.S., Howell, P.L.
J.Biol.Chem.