CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Probable udp-n-acetylglucosamine 2-epimerase protein

Enzyme Information

5.1.3.14
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).
based on mapping to UniProt Q58899
UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-mannosamine.
-!- This bacterial enzyme catalyzes the reversible interconversion of UDP-GlcNAc and UDP-ManNAc. -!- The latter is used in a variety of bacterial polysaccharide biosyntheses. -!- Cf. EC 3.2.1.183.

UniProtKB Entries (1)

Q58899
WECB_METJA
Methanocaldococcus jannaschii DSM 2661
UDP-N-acetylglucosamine 2-epimerase

PDB Structure

PDB 4NES
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc.
Chen, S.C., Huang, C.H., Yang, C.S., Liu, J.S., Kuan, S.M., Chen, Y.
Proteins