CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.120 | Four Helix Bundle (Hemerythrin (Met), subunit A) |
|
1.20.120.10 | Cytochrome c/b562 |
Domain Context
CATH Clusters
| Superfamily | Cytochrome c/b562 |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| Q99835 |
SMO_HUMAN
Homo sapiens
Smoothened homolog
|
| Q0SXH8 |
Q0SXH8_SHIF8
Shigella flexneri 5 str. 8401
Cytochrome b(562)
|
PDB Structure
| PDB | 4N4W |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.
Nat Commun
|