CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Histone acetyltransferase p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q92793
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

P62805
H4_HUMAN
Homo sapiens
Histone H4

PDB Structure

PDB 4N3W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP.
Plotnikov, A.N., Yang, S., Zhou, T.J., Rusinova, E., Frasca, A., Zhou, M.M.
Structure