CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Mixed lineage kinase domain-like pseudokinase

Enzyme Information

UniProtKB Entries (1)

Q8NB16
MLKL_HUMAN
Homo sapiens
Mixed lineage kinase domain-like protein

PDB Structure

PDB 4MWI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL.
Murphy, J.M., Lucet, I.S., Hildebrand, J.M., Tanzer, M.C., Young, S.N., Sharma, P., Lessene, G., Alexander, W.S., Babon, J.J., Silke, J., Czabotar, P.E.
Biochem.J.