CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.25.160
Functional Family Aspartoacylase

Enzyme Information

3.5.1.15
Aspartoacylase.
based on mapping to UniProt P45381
N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate.

UniProtKB Entries (1)

P45381
ACY2_HUMAN
Homo sapiens
Aspartoacylase

PDB Structure

PDB 4MRI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Wijayasinghe, Y.S., Pavlovsky, A.G., Viola, R.E.
Biochemistry