CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10490 | Glucose-6-phosphate isomerase like protein; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Glucose-6-phosphate isomerase like protein; domain 1 |
| Functional Family | Glucokinase regulatory protein |
Enzyme Information
UniProtKB Entries (1)
| Q14397 |
GCKR_HUMAN
Homo sapiens
Glucokinase regulatory protein
|
PDB Structure
| PDB | 4MQU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
J.Med.Chem.
|