CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosyl hydrolase domain; family 39
Functional Family Alpha-L-iduronidase

Enzyme Information

3.2.1.76
L-iduronidase.
based on mapping to UniProt P35475
Hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate.

UniProtKB Entries (1)

P35475
IDUA_HUMAN
Homo sapiens
Alpha-L-iduronidase

PDB Structure

PDB 4MJ2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase.
Bie, H., Yin, J., He, X., Kermode, A.R., Goddard-Borger, E.D., Withers, S.G., James, M.N.
Nat.Chem.Biol.