1 keywords

CATH Domain 4m5tG00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.790  

Domain Context

CATH Clusters

Superfamily 2.60.40.790
Functional Family

Enzyme Information

UniProtKB Entries (1)

P02511
CRYAB_HUMAN
Homo sapiens
Alpha-crystallin B chain

PDB Structure

PDB 4M5T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Hochberg, G.K., Ecroyd, H., Liu, C., Cox, D., Cascio, D., Sawaya, M.R., Collier, M.P., Stroud, J., Carver, J.A., Baldwin, A.J., Robinson, C.V., Eisenberg, D.S., Benesch, J.L., Laganowsky, A.
Proc.Natl.Acad.Sci.USA