CATH Classification

Domain Context

CATH Clusters

Superfamily ornithine cyclodeaminase, domain 1
Functional Family

Enzyme Information

1.5.1.51
N-((2S)-2-amino-2-carboxyethyl)-L-glutamate dehydrogenase.
based on mapping to UniProt A0A0H3K9Y6
N-((2S)-2-amino-2-carboxyethyl)-L-glutamate + NAD(+) + H(2)O = 2-oxoglutarate + L-2,3-diaminopropanoate + NADH.
-!- The enzyme, characterized from the bacterium Staphylococcus aureus, is involved in the biosynthesis of the siderophore staphyloferrin B.

UniProtKB Entries (1)

A0A0H3K9Y6
A0A0H3K9Y6_STAAE
Staphylococcus aureus subsp. aureus str. Newman
Ornithine cyclodeaminase

PDB Structure

PDB 4M54
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor.
Kobylarz, M.J., Grigg, J.C., Takayama, S.J., Rai, D.K., Heinrichs, D.E., Murphy, M.E.
Chem.Biol.