CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.8.1080
Functional Family N-acetylmuramic acid 6-phosphate etherase

Enzyme Information

4.2.1.126
N-acetylmuramic acid 6-phosphate etherase.
based on mapping to UniProt P44862
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate = N-acetylmuramate 6-phosphate + H(2)O.
-!- This enzyme, along with EC 2.7.1.170, is required for the utilization of anhydro-N-acetylmuramic acid in proteobacteria. -!- The substrate is either imported from the medium or derived from the bacterium's own cell wall murein during cell wall recycling. -!- Formerly EC 4.2.1.n1.

UniProtKB Entries (1)

P44862
MURQ_HAEIN
Haemophilus influenzae Rd KW20
N-acetylmuramic acid 6-phosphate etherase

PDB Structure

PDB 4M0D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor.
Hadi, T., Hazra, S., Tanner, M.E., Blanchard, J.S.
Biochemistry