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1 keywords

CATH Domain 4lzoA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family

Enzyme Information

2.7.6.1
Ribose-phosphate diphosphokinase.
based on mapping to UniProt P60891
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- dATP can also act as donor.

UniProtKB Entries (1)

P60891
PRPS1_HUMAN
Homo sapiens
Ribose-phosphate pyrophosphokinase 1

PDB Structure

PDB 4LZO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Chen, P., Liu, Z., Wang, X., Peng, J., Sun, Q., Li, J., Wang, M., Niu, L., Zhang, Z., Cai, G., Teng, M., Li, X.
Plos One
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