CATH Classification

Domain Context

CATH Clusters

Superfamily
Functional Family -

PDB Structure

PDB 4LVB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Zheng, X., Bair, K.W., Bauer, P., Baumeister, T., Bowman, K.K., Buckmelter, A.J., Caligiuri, M., Clodfelter, K.H., Feng, Y., Han, B., Ho, Y.C., Kley, N., Li, H., Liang, X., Liederer, B.M., Lin, J., Ly, J., O'Brien, T., Oeh, J., Oh, A., Reynolds, D.J., Sampath, D., Sharma, G., Skelton, N., Smith, C.C., Tremayne, J., Wang, L., Wang, W., Wang, Z., Wu, H., Wu, J., Xiao, Y., Yang, G., Yuen, P.W., Zak, M., Dragovich, P.S.
Bioorg.Med.Chem.Lett.