CATH Domain 4lsqL01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

Q0ED31_9HIV1

Human immunodeficiency virus 1

Envelope glycoprotein gp160

PDB Structure

PDB	4LSQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Zhou, T., Zhu, J., Wu, X., Moquin, S., Zhang, B., Acharya, P., Georgiev, I.S., Altae-Tran, H.R., Chuang, G.Y., Joyce, M.G., Do Kwon, Y., Longo, N.S., Louder, M.K., Luongo, T., McKee, K., Schramm, C.A., Skinner, J., Yang, Y., Yang, Z., Zhang, Z., Zheng, A., Bonsignori, M., Haynes, B.F., Scheid, J.F., Nussenzweig, M.C., Simek, M., Burton, D.R., Koff, W.C., Mullikin, J.C., Connors, M., Shapiro, L., Nabel, G.J., Mascola, J.R., Kwong, P.D. Immunity