CATH Classification

Domain Context

CATH Clusters

Superfamily Protein prenylyltransferase
Functional Family

Enzyme Information

2.5.1.-
Transferring alkyl or aryl groups, other than methyl groups.
based on mapping to UniProt Q4WP27

UniProtKB Entries (1)

Q4WP27
Q4WP27_ASPFU
Aspergillus fumigatus Af293
CaaX farnesyltransferase alpha subunit Ram2

PDB Structure

PDB 4LNB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
Mabanglo, M.F., Hast, M.A., Lubock, N.B., Hellinga, H.W., Beese, L.S.
Protein Sci.