CATH Classification

Domain Context

CATH Clusters

Superfamily Zinc/RING finger domain, C3HC4 (zinc finger)
Functional Family Histone acetyltransferase

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q92794
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q92794
KAT6A_HUMAN
Homo sapiens
Histone acetyltransferase KAT6A

PDB Structure

PDB 4LJN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Dreveny, I., Deeves, S.E., Fulton, J., Yue, B., Messmer, M., Bhattacharya, A., Collins, H.M., Heery, D.M.
Nucleic Acids Res.