1 keywords

CATH Domain 4l19A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.390 Collagenase (Catalytic Domain)
Homologous Superfamily 3.40.390.10 Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family Collagenase 3

Enzyme Information

3.4.24.-
Metalloendopeptidases.
based on mapping to UniProt P45452

UniProtKB Entries (1)

P45452
MMP13_HUMAN
Homo sapiens
Collagenase 3

PDB Structure

PDB 4L19
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro.
Spicer, T.P., Jiang, J., Taylor, A.B., Choi, J.Y., Hart, P.J., Roush, W.R., Fields, G.B., Hodder, P.S., Minond, D.
J.Med.Chem.