CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family | Cystathionine gamma-synthase |
Enzyme Information
| 2.5.1.48 |
Cystathionine gamma-synthase.
based on mapping to UniProt P56069
O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate.
-!- Also reacts with H(2)S and methanethiol as replacing agents, producing homocysteine and methionine, respectively. -!- In the absence of thiol, can also catalyze beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia. -!- Formerly EC 4.2.99.9.
|
UniProtKB Entries (1)
| P56069 |
METB_HELPY
Helicobacter pylori 26695
Cystathionine gamma-synthase
|
PDB Structure
| PDB | 4L0O |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure determination of cystathionine gamma-synthase from Helicobacter pylori
To be Published
|