CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.920 | Histone Acetyltransferase; Chain A |
|
1.20.920.10 | Bromodomain-like |
Domain Context
CATH Clusters
| Superfamily | Bromodomain-like |
| Functional Family | Bromodomain-containing protein 4 |
Enzyme Information
UniProtKB Entries (1)
| O60885 |
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4
|
PDB Structure
| PDB | 4KV1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Brd4 maintains constitutively active NF-kappa B in cancer cells by binding to acetylated RelA.
Oncogene
|