CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.47.10
Functional Family 3-oxoacyl-ACP synthase III

Enzyme Information

2.3.3.20
Acyl-CoA:acyl-CoA alkyltransferase.
based on mapping to UniProt Q8PDX2
2 an acyl-CoA + H(2)O = a (2R)-2-alkyl-3-oxoalkanoate + 2 CoA.
-!- The enzyme, found in certain bacterial species, catalyzes a head- to-head non-decarboxylative Claisen condensation of two acyl-CoA molecules, resulting in formation of a 2-alkyl-3-oxoalkanoic acid. -!- It is part of a pathway for the production of olefins.

UniProtKB Entries (1)

Q8PDX2
OLEA_XANCP
Xanthomonas campestris pv. campestris str. ATCC 33913
Acyl-CoA:acyl-CoA alkyltransferase

PDB Structure

PDB 4KU2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis.
Goblirsch, B.R., Jensen, M.R., Mohamed, F.A., Wackett, L.P., Wilmot, C.M.
J.Biol.Chem.